Help Fund the Next Breakthrough

Your Donation Will be Doubled November 18 – December 2

DIPG/DMG is one of the most aggressive brain cancers, most often diagnosed in young children, but can also be found in adults. Its rapid progression and lack of treatment options make it one of the most devastating diagnoses a family can face. Families are left searching for hope in a landscape where options are heartbreakingly limited.

Despite the odds, we’ve made incredible progress in the last decade. Researchers have identified some of the genetic mutations that cause DIPG, developed groundbreaking therapies like CAR-T, and ONC201 has now become the first-ever FDA-approved treatment for DIPG. This progress has given hope to so many, and we can’t stop when momentum is on our side.

Securing federal research funding has become more difficult than ever, and the field relies on private foundations like ChadTough Defeat DIPG to keep vital research moving forward. Your support ensures that we remain the most reliable source of funding for DIPG and DMG research. It also allows us to continue helping families through our My DIPG Navigator program, which connects them with experts and information when they need it most.

Investing in DIPG research does more than fight one disease. The discoveries being made are already transforming treatment for breast, lung, colon, pancreatic, and other cancers. The progress we are making now is unprecedented, but it won’t continue without funding. Your support could be what helps push the next breakthrough forward, not just for DIPG, but for cancer patients everywhere.

Our matching donors have committed to matching all donations from November 18-December 2, 2025, up to $250,000, to help us accelerate our path to a cure. Meaning, every $1 you donate will be worth $2! Double your impact by donating today.